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This slope in turn is usedto computeanothervalue of ,vand anotherslopeat the midpoint: : r(0..5): 2 + 1.211299(0.5) 4. 108649 5) - 1e08(0 - 0.-5(4. : k7 : .f (0.5,4.108649) 108649) 3.912974 Next. this siopeis usedto compute valueof .r, a and a slopeat the end of the interval; : : ,y(1.0) 2 + 3.912914(1.0) 5.912974 -) 4 e 0 8 ( t 0 ) . 5 ( 5 . 9 1 2 9 7 4 ) : 5 . 9 4 5 6 7 7 -0 ka: f (1.0,5.9|2974 Finally,the four slopeestimates combined yield an average This average are to slope. slope is thenusedto rnakethe final prediction the end of the interval. at Q: 2e9)+ 2(3.91291 + 5.945611 : 4.201031 1) [3 + 2(1.211 ]

Thus, the two slopes[Eqs.(20.14)and (20.16)] can be combinedto obtainan average slope for the interval; * -, _ /(r,,-r'r) ,f(rr+r,r',9+r)

TradeStation Strategy Performance Report VL4% Daily 20 dma (12/23/1992-11/29/2002)

Table C-2.

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D e t e r m i n i n g o l y n o m i oC o e f f i c i e n t w i t h S i m u l t o n e o uE q u o t i o n s P l s s Problem Stotemeni. Suppose that we want to determine coefficients the parabola, the of \ l5. : . f ( x ) : p t . t 2 1 p 2 - + p l , t h a t p a s s e s t h r o u g h t h e l a s t t h r e e d e n s i t y v a l u e s f r o m T la b l e

Nd:YAG lasers have also been explored as treatment possibilities for keloids. In 1984, Abergel and colleagues treated keloid fibroblast cultures and control cultures with the CW 1064-nm Nd:YAG. Keloid broblasts initially had twice the amount of collagen production as the controls, and when treated with a uence of 700 J/cm2, collagen production dropped to approximately the same level measured in controls. A uence of 1100 J/cm2 further inhibited collagen production in keloids. Abergel and colleagues reported collagen production was notably repressed with the 1100 J/cm2 uence, without affecting the viability or DNA replication of the cells. However, collagen production was not suppressed in controls using lower fluences.27 Based on the fibroblast culture studies, a case study of Nd:YAG treatment of resistant keloids showed progressing lightening and flattening, with no recurrence noted at the 3-year follow up.27 Researchers believed that the Nd:YAG laser most likely acts through a process involving a subtle biological modulation of the broblast functions, resulting in selective suppression of the procollagen production by the cells. The

Emotional Lability It is a commonplace clinical experience that cerebral diseases of many types, seemingly without respect to location, weaken the mechanism of control of emotional expression a mechanism that has been acquired over years of maturation The degree to which this pertains varies with gender and ethnicity and has more to do with social norms than with biology In certain cultures, women are permitted to cry in public but men are not In the realm of neurologic disease, a patient whose cerebrum has been damaged for example, by a series of vascular lesions may suffer the humiliation of crying in public upon meeting an old friend or hearing the national anthem, or of displaying uncontrollable laughter in response to a mildly amusing remark or an attempt to tell a funny story.

There may also be easy vacillation from one state to another, an emotional lability that has for more than a century been accepted as a sign of organic brain disease In this type of emotional disturbance, the response, while excessive, does not reach the degree of forced emotionality of the special form of lability described as pseudobulbar (see below); furthermore, it is appropriate to the stimulus and the affect is congruent with the visceral and motor components of the expression The anatomic substrate is obscure Perhaps lesions of the frontal lobes more than those of other parts of the brain are conducive to this state, but the authors are unaware of a critical clinicoanatomic study that substantiates this impression Emotional lability is a frequent accompaniment of diffuse cerebral diseases such as Alzheimer disease, but these diseases, of course, also involve the limbic cortex.

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